Validated by Science. Guided by Innovation.

At BioEon, every formulation is grounded in science‑backed research and independent validation. Our commitment to transparency means you have access to the same clinical evidence that inspires and guides our product development. From cutting‑edge NAD⁺ precursors to advanced absorption methods, the science speaks for itself.

 

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Modern Evidence for NAD⁺ Precursors & Synergistic Formulation

PubMed: Nicotinamide Riboside – The Current State of Research and Therapeutic Uses

Comprehensive review of NR as a potent NAD⁺ precursor — exploring its biochemical pathways, clinical potential, and emerging applications.

PubMed: NRPT (Nicotinamide Riboside + Pterostilbene) Safely Elevates NAD⁺

Demonstrates how combining NR with pterostilbene sustainably increases NAD⁺ levels in humans — without adverse effects.

Nature: Nicotinamide Riboside is Well‑Tolerated & Elevates NAD⁺ in Older Adults 

Nature‑published study showing NR supplementation safely boosts NAD⁺ in healthy middle‑aged and older adults.

PubMed: Long‑Term NIAGEN (NR Chloride) Use is Safe

A double‑blind, placebo‑controlled trial confirming NR’s long‑term safety profile and favorable metabolism.

PubMed: NR Enhances Skeletal Muscle NAD⁺ & Reduces Inflammation in Aging

Clinical evidence that NR supplementation restores NAD⁺ metabolome in aged muscle, improves gene expression, and reduces inflammation.

PMC: NRPT Accelerates Recovery from Muscle Injury in Elderly

Randomized trial showing NR + pterostilbene supplementation enhances recovery after experimental muscle injury in older adults.

 

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Pterostilbene: Additional Clinical Evidence

PMC: Pterostilbene Improves Metabolic Parameters

Placebo‑controlled trial confirming pterostilbene’s role in supporting healthy lipid and glucose metabolism.

 

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Modern Evidence for Advanced Absorption & Rectal Delivery

Bentham Science Journal – A Modern Review of Rectal Drug Delivery (2023)

Explores the evolution of rectal delivery systems — highlighting mucoadhesive, slow‑release technologies that increase bioavailability and reduce systemic side effects.

SpringerLink – Rectal Infusion in Modern Clinical Practice (2024)

Details how modern hospitals use rectal infusion for safe, effective delivery — especially when IV access is limited or delayed.